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Metabolism & organs

Ceruloplasmin test

Copper-carrying protein; low levels may suggest Wilson's disease, high levels can reflect inflammation or estrogen state.

At a glance

Price

$13.00

Priced per marker, with baseline labs included. You’ll see your total before you pay.

Results

In about 5 days

Most results are ready in about 5 days. Some specialty markers can take up to 21 days.

Preparation

Check before your draw

This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.

Blood draw

Walk in at Quest

Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.

What it measures

Ceruloplasmin is the main protein that carries copper in your blood. Your liver makes it, and low levels may point to problems with how your body handles copper.

Why it matters for women

Estrogen can raise ceruloplasmin, so levels can run higher in pregnancy and with estrogen birth control or hormone therapy. That can make a low level look normal when checking for Wilson disease, an inherited condition where copper builds up. A copper shortage, which can follow weight-loss surgery, can lower it.

You might check it if…

  • a doctor is checking for Wilson disease or copper buildup
  • liver problems started at a young age without a clear cause
  • you’ve had weight-loss surgery and feel numbness or unsteadiness
  • a family member has Wilson disease

What your result may mean

High Ceruloplasmin: what it may mean

High ceruloplasmin can happen with inflammation, pregnancy, oral estrogen or certain liver conditions, since this copper-carrying protein can rise when your body responds to illness or injury. Estrogen birth control and hormone therapy can raise it, so levels can run higher in pregnancy and on these medicines. That rise can make a truly low level look normal when a clinician is checking for Wilson disease, an inherited copper condition. You may feel nothing from the high value itself, and inflammation and liver tests can help find the reason.

Low Ceruloplasmin: what it may mean

Low ceruloplasmin may point to Wilson disease (Wilson's disease), an inherited condition where copper builds up in the liver, brain and eyes, or to a severe copper shortage (copper deficiency), which can follow weight-loss surgery. Wilson disease can cause liver problems, tremors or mood changes, while a copper shortage can cause anemia, numbness or trouble walking. Heavy protein loss can also lower it. A clinician may check copper in your blood and urine, because this result can't settle the question alone.

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No insurance required · HSA/FSA eligible · No subscription

These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.