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Metabolism & organs
GGT test
Gamma-glutamyl transferase. Liver enzyme sensitive to alcohol use and bile-duct obstruction; can rise in fatty liver disease.
At a glance
In about 5 days
Most results are ready in about 5 days. Some specialty markers can take up to 21 days.
Check before your draw
This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.
Walk in at Quest
Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.
What it measures
GGT is an enzyme, a type of protein, found mostly in your liver and the tubes that drain it. It can rise early when the liver is under strain, such as from alcohol or fat buildup.
Why it matters for women
Women tend to develop alcohol-related liver damage after less drinking than men, and GGT can rise early with regular drinking. It can also help show whether a high alkaline phosphatase result comes from the liver or from bone. In pregnancy, GGT may not rise the way alkaline phosphatase does, which can help sort out the cause.
You might check it if…
- you drink alcohol regularly and want to see its effect
- your alkaline phosphatase result came back high
- you live with PCOS or diabetes, which raise fatty liver risk
What your result may mean
High GGT: what it may mean
High GGT may point to bile duct injury, fatty liver, alcohol use or medicines that can stress the liver. It can rise early with regular drinking, and women can develop alcohol-related liver damage after less drinking than men. GGT can also help show whether a high alkaline phosphatase comes from the liver or from bone, since a high GGT may point to the liver. Many people may have no symptoms, and some seizure medicines can raise it without any liver damage. ALT and AST results can help narrow down what is going on.
Low GGT: what it may mean
Low GGT can be a normal finding. Next to a high alkaline phosphatase, a low or normal GGT may point to bone rather than the liver, and pregnancy can be another reason for that pattern. Birth control pills can nudge GGT down, and it can run lower in pregnancy. A low value can't rule out every liver problem, because some liver conditions may not raise it, so a clinician may still read it with your other liver results.
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These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.