$33.00
Priced per marker, with baseline labs included. You’ll see your total before you pay.
Heart & circulation
Lp-PLA2 activity test
Lipoprotein-associated phospholipase A2. Inflammation marker specific to vascular plaque; elevated levels can increase cardiovascular event risk.
At a glance
In about 5 days
Most results are ready in about 5 days. Some specialty markers can take up to 21 days.
Check before your draw
This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.
Walk in at Quest
Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.
What it measures
This enzyme, a type of protein, is tied to inflammation inside your artery walls, where plaque, a fatty buildup, can form. Higher activity can be one sign of greater risk for heart disease and stroke.
Why it matters for women
Heart disease is the leading cause of death in women, and risk can climb after menopause. Standard cholesterol tests don’t show inflammation in the arteries, so this test can add detail when your risk is hard to judge.
You might check it if…
- heart disease or stroke runs in your family
- your cholesterol results are borderline
- you’re in perimenopause or past menopause
- you’ve had preeclampsia or high blood pressure in pregnancy
What your result may mean
High Lp-PLA2 activity: what it may mean
High Lp-PLA2 activity may point to inflammation in your artery walls, and it can add to your risk of heart disease and stroke apart from your LDL level. Plaque can build up silently, so you may feel fine. This enzyme can travel on LDL particles, so high cholesterol can push it up too. Heart risk can climb after menopause, so this test may help when your other numbers leave your risk unclear.
Low Lp-PLA2 activity: what it may mean
Low Lp-PLA2 activity may be a favorable result, since it may mean less inflammation in your artery walls. It can't rule out heart disease, so cholesterol, blood pressure, blood sugar, smoking and family history may still matter. Statins and other cholesterol-lowering medicines can lower it, so a low result on treatment may partly come from that. It may be one small piece of a bigger heart-risk review, especially after menopause, when risk can start to climb.
Get started
Stop guessing. Start testing.
Answer a few questions. We’ll suggest tests linked to how you feel, with a clear price for every test.
No insurance required · HSA/FSA eligible · No subscription
These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.