Skip to content
Create account to build your panelHelp me choose
Blood & iron

MCHC test

Mean corpuscular hemoglobin concentration. The concentration of hemoglobin within red cells; helps distinguish types of anemia. Included with every panel.

At a glance

Price

Included with every panel

Baseline labs come free with any panel you build.

Results

In about 5 days

Most results are ready in about 5 days. Some specialty markers can take up to 21 days.

Preparation

Check before your draw

This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.

Blood draw

Walk in at Quest

Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.

What it measures

MCHC shows how tightly packed hemoglobin, the oxygen-carrying protein, is inside your red blood cells. Cells with less of it can look paler, which may be one sign of low iron.

Why it matters for women

Low MCHC, which may mean paler red cells, can be a classic sign of low iron, which is common in women because of periods and pregnancy. It can change later than other red cell measures, so it’s read together with them.

You might check it if…

  • your periods are heavy or last a long time
  • you often feel tired, weak or short of breath
  • you’re pregnant, planning to be, or recently gave birth
  • a past test showed low iron or anemia

What your result may mean

High MCHC: what it may mean

High MCHC may mean hemoglobin is packed unusually tightly inside your red blood cells, a finding that can be uncommon. It can occur in hereditary spherocytosis, an inherited condition that makes red cells round and fragile, or in autoimmune hemolytic anemia, when the immune system breaks down red cells. Certain lab interferences can also raise the number, including cold agglutinins (antibodies that clump red cells), very fatty blood or a damaged sample. When red cells are breaking down, you may notice tiredness, yellowish skin or dark urine. A clinician may repeat the test or review a blood smear before reading much into it.

Low MCHC: what it may mean

Low MCHC may mean your red blood cells hold less hemoglobin than expected and look paler (hypochromic), classically from iron deficiency. It can also occur with thalassemia, an inherited blood condition, or with long-term illness. Periods and pregnancy can use up iron, so women can be more prone to this result. MCHC can change later than MCV and other red cell measures, so it may look normal early in iron deficiency. Symptoms can include tiredness, pale skin, headaches or shortness of breath with activity, although a mild drop may go unnoticed.

Get started

Stop guessing. Start testing.

Answer a few questions. We’ll suggest tests linked to how you feel, with a clear price for every test.

No insurance required · HSA/FSA eligible · No subscription

These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.