$35.00
Priced per marker, with baseline labs included. You’ll see your total before you pay.
Bone health
P1NP test
Procollagen type 1 N-terminal propeptide. Bone formation marker (P1NP); can rise with new bone formation.
At a glance
In about 5 days
Most results are ready in about 5 days. Some specialty markers can take up to 21 days.
Check before your draw
This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.
Walk in at Quest
Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.
What it measures
When your body builds new bone, it releases a small protein called P1NP. Measuring it can show how actively new bone is being made.
Why it matters for women
Bone loss can speed up in the years around menopause, and osteoporosis is much more common in women. P1NP can show the building side of bone renewal. Paired with CTx, which can show breakdown, it can help a doctor see how your bones are changing and how they respond over time.
You might check it if…
- a bone density scan showed thinning bones
- you’ve broken a bone more easily than expected
- a doctor is tracking how your bones respond over time
What your result may mean
High P1NP: what it may mean
High P1NP may mean your body is building new bone at a faster pace. It can happen during teen growth, while a fracture heals, with Paget's disease of bone, or as a bone-building osteoporosis medicine takes effect. Bone turnover can also speed up around menopause, so P1NP may rise along with CTx. Paget's disease can bring bone pain, while other reasons may cause no symptoms. A high value can't show on its own that bones are getting stronger, so a bone density scan can add what this test leaves out.
Low P1NP: what it may mean
Low P1NP may mean your body is making less new bone. It can be an expected effect of bisphosphonates, which can slow bone turnover, and it can also happen with age-related bone loss. Long-term steroid medicines can reduce bone building as well. Slow bone building can be silent, with nothing to feel. Change over time can say more than one number, so an earlier result or a CTx level can help.
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These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.