$22.00
Priced per marker, with baseline labs included. You’ll see your total before you pay.
Brain & nervous system
17-Hydroxyprogesterone test
Primary screening test for non-classic congenital adrenal hyperplasia (NCAH) due to 21-hydroxylase deficiency.
At a glance
In about 5 days
Most results are ready in about 5 days. Some specialty markers can take up to 21 days.
Check before your draw
This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.
Walk in at Quest
Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.
What it measures
A hormone your adrenal glands and ovaries make on the way to other hormones, including cortisol. High levels can be a sign of an inherited condition that can cause extra androgens, hormones like testosterone.
Why it matters for women
A mild inherited adrenal condition called non-classic CAH can cause irregular periods, acne, extra hair growth, and trouble getting pregnant, much like PCOS. This test can help tell the two apart. Levels can change through the day and across your cycle, so it’s best checked in the morning, in the days after your period starts.
You might check it if…
- your periods are irregular or often far apart
- you’ve noticed extra facial or body hair or stubborn acne
- a doctor has mentioned PCOS
- you’re having trouble getting pregnant
What your result may mean
High 17-Hydroxyprogesterone: what it may mean
High 17-hydroxyprogesterone may point to classic or non-classic congenital adrenal hyperplasia (CAH), an inherited condition that can involve the 21-hydroxylase enzyme and lead to extra androgens. In women, non-classic CAH can look a lot like PCOS, and some may notice irregular periods, acne, extra hair growth or trouble getting pregnant. Levels can also run higher after ovulation and during pregnancy, and they can change through the day, so timing may sway the result. A clinician may repeat the test in the morning or add an ACTH stimulation test.
Low 17-Hydroxyprogesterone: what it may mean
Low 17-hydroxyprogesterone may be a normal result and may need no follow-up. Levels can sit lower in the first half of the menstrual cycle and later in the day, because this hormone can swing with ovulation and the body's daily rhythm. Steroid medicines such as prednisone or dexamethasone can also lower it. A sample drawn in the afternoon can read low, so a low value then can't rule out a mild form of congenital adrenal hyperplasia (CAH), which can cause irregular periods or extra hair.
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These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.