$7.00
Priced per marker, with baseline labs included. You’ll see your total before you pay.
Hormones & reproductive
Estradiol test
E2. Primary estrogen during reproductive years; produced by ovaries.
At a glance
In about 5 days
Most results are ready in about 5 days. Some specialty markers can take up to 21 days.
Best at a set time of day or cycle day
Contact us before your draw if you’re not sure.
Walk in at Quest
Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.
What it measures
Estradiol is the main form of estrogen during your reproductive years, made mostly by your ovaries. Your level can rise and fall a lot through your cycle, so when you test matters.
Why it matters for women
Estradiol shapes your periods, fertility and bone health. It can help explain missed or irregular periods, trouble getting pregnant, or symptoms like hot flashes. In perimenopause, the years leading up to menopause, it can swing up and down, so one result doesn’t tell the whole story.
You might check it if…
- your periods have become irregular or stopped
- you’re trying to get pregnant
- you’re getting hot flashes, night sweats or vaginal dryness
- a doctor is tracking your levels on hormone therapy
What your result may mean
High Estradiol: what it may mean
High estradiol may be normal around ovulation, when levels can peak late in the follicular phase. Outside that window, it can point to estrogen excess, an ovarian tumor, or estrogen-containing supplements or hormone therapy. Levels can also climb in pregnancy and during fertility treatment, and they can swing widely in perimenopause. Breast tenderness, bloating or heavy or irregular periods can occur, or a high level may pass unnoticed. Cycle day can sway the result, and biotin can interfere with some estradiol tests.
Low Estradiol: what it may mean
Low estradiol may be normal after menopause, and it can also run low early in your cycle. Before menopause, it may suggest ovarian insufficiency or hypothalamic amenorrhea, when stress, under-eating or hard training can stop periods. Breastfeeding and hormonal birth control can lower your own estradiol too. Hot flashes, night sweats, vaginal dryness, missed periods or trouble sleeping can appear. Long-lasting low estrogen can affect bone health, so a clinician may look at FSH and your cycle history.
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These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.