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Allergy & immunology

IgG test

Immunoglobulin G. Main antibody class; can reflect long-term immune memory and immune competence.

At a glance

Price

$12.00

Priced per marker, with baseline labs included. You’ll see your total before you pay.

Results

In about 5 days

Most results are ready in about 5 days. Some specialty markers can take up to 21 days.

Preparation

Check before your draw

This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.

Blood draw

Walk in at Quest

Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.

What it measures

IgG is your body’s most common antibody, and it carries long-term protection from past infections and vaccines. This can show whether your overall level runs low, normal, or high.

Why it matters for women

IgG is the only antibody that crosses the placenta, which is how a mother passes protection to her baby before birth. High levels can come with autoimmune conditions that are more common in women, like lupus and Sjögren’s. Low levels can mean more frequent or stubborn infections.

You might check it if…

  • you get infections often, or they’re slow to clear
  • a doctor is looking into lupus, Sjögren’s, or a similar condition
  • a blood test showed unusually high protein levels

What your result may mean

High IgG: what it may mean

High IgG may point to a long-lasting infection, an autoimmune condition, chronic liver disease or a rise in one single type of antibody (monoclonal gammopathy), including multiple myeloma. Autoimmune conditions tied to high IgG, such as lupus and Sjögren's, can be more common in women, and they may bring joint pain, tiredness, or dry eyes and mouth. A mild rise can also go unnoticed. Serum protein electrophoresis can tell a broad rise apart from one made by a single group of cells.

Low IgG: what it may mean

Low IgG may point to a primary immunodeficiency such as common variable immune deficiency (CVID), or to losing protein through the kidneys or gut. Medicines that calm the immune system, such as steroids, can lower it too. Levels can also dip in pregnancy as extra fluid dilutes the blood. Frequent or stubborn sinus, chest or ear infections may be a clue, and vaccines may not work as well. IgG can cross the placenta to protect a baby, so this result may matter if you're planning a pregnancy.

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No insurance required · HSA/FSA eligible · No subscription

These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.