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Allergy & immunology

Tryptase test

Mast cell enzyme; can be elevated in mastocytosis, anaphylaxis, and mast cell activation syndrome.

At a glance

Price

$45.00

Priced per marker, with baseline labs included. You’ll see your total before you pay.

Results

In about 5 days

Most results are ready in about 5 days. Some specialty markers can take up to 21 days.

Preparation

Check before your draw

This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.

Blood draw

Walk in at Quest

Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.

What it measures

Tryptase is released by mast cells, immune cells that set off allergic reactions. It can jump during a severe reaction, while a level taken on an ordinary day can show your usual baseline.

Why it matters for women

Severe allergic reactions and repeated bouts of flushing, hives, or stomach cramps can be hard to explain. A tryptase level on an ordinary day gives your doctor a baseline to compare against, and a high one can point to a mast cell condition worth a closer look.

You might check it if…

  • you’ve had a severe allergic reaction
  • you often get flushing, hives, or cramps without a clear trigger
  • you react strongly to insect stings

What your result may mean

High Tryptase: what it may mean

High tryptase may mean mast cells, immune cells that set off allergic reactions, have released their contents. A sharp rise soon after a severe reaction may point to anaphylaxis, while a high level on an ordinary day may point to mastocytosis, mast cell activation syndrome or an inherited trait called hereditary alpha-tryptasemia. Kidney disease can raise it too. Flushing, hives, stomach cramps and faintness can all come with mast cell problems. A result taken during symptoms can say more when it's compared with your baseline.

Low Tryptase: what it may mean

Low tryptase may be a normal result and may need no follow-up. It can't rule out allergy, because many allergic reactions, especially to food, can happen without a clear rise. A sample taken many hours after a reaction can also read low, since tryptase can fall back quickly. If you get repeated flushing, hives or stomach cramps, a clinician may look for a rise above your baseline during an episode rather than rely on one quiet-day number.

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No insurance required · HSA/FSA eligible · No subscription

These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.