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Red blood cell antibody screen test

Screens for red blood cell antibodies that can cause transfusion reactions or hemolytic disease of the newborn.

At a glance

Price

$12.00

Priced per marker, with baseline labs included. You’ll see your total before you pay.

Results

In about 5 days

Most results are ready in about 5 days. Some specialty markers can take up to 21 days.

Preparation

Check before your draw

This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.

Blood draw

Walk in at Quest

Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.

What it measures

Your body can make antibodies, immune proteins, against red blood cells that aren’t your own, such as after a transfusion or pregnancy. This screen looks for them, and the lab identifies and measures any it finds.

Why it matters for women

In pregnancy, some of these antibodies can cross to the baby and attack the baby’s red blood cells, which can leave the baby with too few of them (anemia). That’s why this screen is a routine part of prenatal care. Antibodies can form after an earlier pregnancy, a miscarriage or a blood transfusion.

You might check it if…

  • you’re pregnant or planning a pregnancy
  • your blood type is Rh negative, like O negative
  • you’ve had a blood transfusion before
  • a past pregnancy involved red blood cell antibodies

What your result may mean

High Red blood cell antibody screen: what it may mean

A positive antibody screen may mean unexpected antibodies against red blood cells are present, which can matter for transfusion safety and pregnancy care. These antibodies can form after an earlier pregnancy, a miscarriage or a blood transfusion. In pregnancy, some can cross to the baby and attack the baby's red cells (hemolytic disease of the fetus and newborn), so extra monitoring may be needed. A recent Rh immune globulin (RhoGAM) shot can also turn this screen positive for a while. The lab can then identify the antibody and measure it, and you may feel nothing at all.

Low Red blood cell antibody screen: what it may mean

A negative antibody screen may mean no clinically significant red blood cell antibodies are present in this sample. It can't promise none will form later, since a new pregnancy or transfusion can trigger them. Levels can also sit too low for the screen to pick up. That's why a clinician may repeat this test later in pregnancy, especially if your blood type is Rh negative, or before a transfusion. A negative screen can be reassuring when you're planning for a birth or surgery.

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No insurance required · HSA/FSA eligible · No subscription

These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.