$16.00
Priced per marker, with baseline labs included. You’ll see your total before you pay.
Brain & nervous system
11-Deoxycortisol test
Steroid precursor that can help identify 11-beta-hydroxylase deficiency, a form of congenital adrenal hyperplasia (CAH).
At a glance
In about 5 days
Most results are ready in about 5 days. Some specialty markers can take up to 21 days.
Check before your draw
This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.
Walk in at Quest
Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.
What it measures
A hormone your adrenal glands, small glands on top of your kidneys, make on the way to cortisol, your main stress hormone. A buildup can mean one step in that process isn’t working as it should.
Why it matters for women
An inherited adrenal condition called congenital adrenal hyperplasia can make the body overproduce androgens, hormones like testosterone. In women that can mean irregular periods, acne, extra facial hair, or trouble getting pregnant, which can look a lot like PCOS. This test checks for one of the rarer forms.
You might check it if…
- your periods are irregular and you’ve noticed extra hair or acne
- you’ve had high blood pressure from a young age
- a doctor is looking into an inherited adrenal condition
What your result may mean
High 11-Deoxycortisol: what it may mean
High 11-deoxycortisol may point to 11-beta-hydroxylase deficiency, an inherited form of congenital adrenal hyperplasia (CAH) that can block the last step in making cortisol. When that step is blocked, the adrenal glands can make extra androgens, hormones like testosterone, and women may notice irregular periods, acne or extra facial hair. Some people with this condition can also have high blood pressure. Levels can also rise on purpose during a metyrapone test, which blocks cortisol production, so a high number may mean something different after that test.
Low 11-Deoxycortisol: what it may mean
Low 11-deoxycortisol may be expected on a routine blood draw, because this hormone can stay low unless a metyrapone test has been done. On its own, a low baseline result may not be a concern. After metyrapone, a level that stays low may mean the adrenal glands or pituitary aren't responding as they should, as in adrenal insufficiency. Tiredness, dizziness and weight loss can come with that condition. Steroid medicines can also lower adrenal hormones, so this result may be easier to read next to cortisol and ACTH.
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These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.