$14.00
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Brain & nervous system
17-Hydroxypregnenolone test
Adrenal steroid intermediate; used to evaluate 3-beta-hydroxysteroid dehydrogenase deficiency and adrenal androgen production.
At a glance
In about 5 days
Most results are ready in about 5 days. Some specialty markers can take up to 21 days.
Check before your draw
This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.
Walk in at Quest
Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.
What it measures
Your adrenal glands, which sit on top of your kidneys, pass this hormone along as they make other hormones. A buildup can point to a hold-up at one step in that chain.
Why it matters for women
Acne, thinning scalp hair, or extra facial hair can be signs of extra androgens, hormones like testosterone, which can come from the ovaries or the adrenal glands. Along with other hormone tests, this one can help show whether a rare inherited adrenal condition is involved.
You might check it if…
- you’ve noticed acne, thinning hair, or extra facial or body hair
- your periods are irregular and the cause isn’t clear
- a doctor is looking into how your adrenal glands make hormones
What your result may mean
High 17-Hydroxypregnenolone: what it may mean
High 17-hydroxypregnenolone may point to congenital adrenal hyperplasia (CAH), a group of inherited conditions that can change how the adrenal glands make hormones. A rare form called 3-beta-hydroxysteroid dehydrogenase deficiency can make this hormone build up behind a blocked step. In women, extra androgens, hormones like testosterone, can cause irregular periods, acne, thinning scalp hair or extra facial hair, which can look like PCOS. Because a mild rise can be hard to interpret alone, 17-hydroxyprogesterone and DHEA results can add useful context.
Low 17-Hydroxypregnenolone: what it may mean
Low 17-hydroxypregnenolone may be expected, and it may not mean much on its own. This hormone is a stepping stone toward other hormones, so only a small amount can be present in the blood at any time. Steroid medicines such as prednisone can quiet the adrenal glands and may lower it further. A low value can't rule out other hormone problems, so irregular periods, acne or extra hair may still need a closer look.
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These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.