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Albumin/Globulin Ratio test

The ratio of albumin to all other blood proteins (globulins); helps interpret total protein and flag liver, kidney, or immune disorders. Included with every panel.

At a glance

Price

Included with every panel

Baseline labs come free with any panel you build.

Results

In about 5 days

Most results are ready in about 5 days. Some specialty markers can take up to 21 days.

Preparation

Check before your draw

This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.

Blood draw

Walk in at Quest

Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.

What it measures

Compares the two main groups of protein in your blood: albumin, made by your liver, and globulins, which include the antibodies that fight infection. The balance can hint at liver, kidney or immune changes.

Why it matters for women

Autoimmune conditions, where the immune system attacks the body by mistake, are much more common in women. Some, such as lupus, can raise globulins and lower this ratio, and pregnancy can naturally lower albumin, which can shift it too. The ratio is a clue rather than an answer, so it’s read alongside your other protein results.

You might check it if…

  • a doctor mentioned lupus or another autoimmune condition
  • your total protein result was high or low
  • you’ve had joint pain, rashes or ongoing dry eyes and mouth
  • you get infections often or they’re slow to clear

What your result may mean

High Albumin/Globulin Ratio: what it may mean

A high albumin/globulin (A/G) ratio may reflect low globulins, which can be seen in some immune deficiencies or genetic conditions. Because globulins include the antibodies that fight infection, some people with low levels may get infections more easily, while others may notice nothing. A mildly high ratio may mean little when your total protein looks normal. Medicines that calm the immune system can lower globulins as well. If the ratio stays high, a clinician may look at your globulin result or check antibody (immunoglobulin) levels.

Low Albumin/Globulin Ratio: what it may mean

A low albumin/globulin (A/G) ratio may point to low albumin, as can happen with liver disease or malnutrition, or to high globulins, as can happen with long-lasting inflammation, infection or a disorder like multiple myeloma. Lupus and other autoimmune conditions can raise globulins, and they can be much more common in women. Pregnancy can naturally lower albumin, which can shift this ratio too. Tiredness or swelling can appear, or you may feel fine. The ratio can't name a reason on its own, so it may be read with your other protein results.

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No insurance required · HSA/FSA eligible · No subscription

These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.