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Hormones & reproductive

Estriol test

Estrogen made by the placenta during pregnancy; low levels may point to fetal/placental dysfunction.

At a glance

Price

$23.00

Priced per marker, with baseline labs included. You’ll see your total before you pay.

Results

In about 5 days

Most results are ready in about 5 days. Some specialty markers can take up to 21 days.

Preparation

Check before your draw

This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.

Blood draw

Walk in at Quest

Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.

What it measures

Estriol is a form of estrogen made in large amounts by the placenta, the organ that nourishes a baby during pregnancy. Outside pregnancy, levels can be very low and the test is rarely useful.

Why it matters for women

In pregnancy, estriol is one of several markers in a screening blood test for certain chromosome conditions, such as Down syndrome. That screen is ordered through your prenatal care, where estriol is read with the other markers and how far along you are. On its own, this test isn’t a pregnancy screen.

You might check it if…

  • a doctor asked for it during your pregnancy care
  • a doctor asked for an estriol level for another reason

What your result may mean

High Estriol: what it may mean

High estriol may be normal in pregnancy, when the placenta can make large amounts and levels can climb as the due date nears. Carrying twins can push it higher too. Outside pregnancy, an abnormally high level can be rare, though hormone creams or other products containing estriol can raise it. On its own, this number can’t show how a pregnancy is going, since it may be read with other markers and how far along you are. It may cause no symptoms that stand apart from normal pregnancy.

Low Estriol: what it may mean

Low estriol in pregnancy may point to a problem with the placenta (placental dysfunction) or fetal complications. In prenatal screening, low estriol can be part of a pattern linked to Down syndrome or trisomy 18, and it can’t settle that question alone. Steroid medicines and a wrong due date can sway the result. Outside pregnancy, levels can be very low, and that may not be a concern. A low value may come with no symptoms, so your prenatal care team may look at the other markers and ultrasound findings.

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No insurance required · HSA/FSA eligible · No subscription

These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.