$36.00
Priced per marker, with baseline labs included. You’ll see your total before you pay.
Autoimmune & inflammation
tTG antibody (IgG) test
Tissue transglutaminase antibody. IgG version used when patient is IgA-deficient.
At a glance
In about 5 days
Most results are ready in about 5 days. Some specialty markers can take up to 21 days.
Check before your draw
This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.
Walk in at Quest
Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.
What it measures
Checks for the IgG type of the main celiac antibody. It’s used mostly when your body makes little IgA, which can make the standard celiac test look normal.
Why it matters for women
Celiac disease is more common in women and may show up as ongoing low iron, early bone thinning, or trouble getting pregnant. Low IgA can be more common in people with celiac, and this IgG version can fill that gap. Like other celiac tests, it works best while you’re still eating gluten.
You might check it if…
- a test showed your IgA is low
- you get bloating or belly pain after eating gluten
- a close relative has celiac disease
What your result may mean
High tTG antibody (IgG): what it may mean
High tTG IgG may point to celiac disease, especially in people with IgA deficiency, who can't make enough of the antibody the standard test looks for. When IgA is normal, this version can be less specific, so a clinician may read it with tTG IgA, total IgA and deamidated gliadin tests. Celiac disease can be more common in women and may appear as ongoing low iron, early bone thinning or trouble getting pregnant. Belly pain or bloating may come with it, though some people may have no gut symptoms.
Low tTG antibody (IgG): what it may mean
Low or negative tTG IgG with a normal IgA level may make celiac disease less of a concern. It can't rule celiac out on its own, especially if you've cut back on gluten, since these antibodies can fall without it. If your total IgA is normal, the tTG IgA test can be the more useful of the two, so a clinician may look at that result first. Ongoing gut symptoms or unexplained low iron may still call for a closer look.
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These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.