$25.00
Priced per marker, with baseline labs included. You’ll see your total before you pay.
Autoimmune & inflammation
CCP antibody (IgG) test
Cyclic citrullinated peptide antibody. Highly specific autoantibody for rheumatoid arthritis; can be positive before symptoms appear.
At a glance
In about 5 days
Most results are ready in about 5 days. Some specialty markers can take up to 21 days.
Check before your draw
This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.
Walk in at Quest
Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.
What it measures
CCP antibodies can be a strong clue for rheumatoid arthritis, a condition where the immune system attacks the lining of the joints. They can show up years before joints start to hurt.
Why it matters for women
Rheumatoid arthritis is more common in women and often starts in midlife or earlier. Many women find it eases during pregnancy, then flares in the months after giving birth. A positive CCP result can help a doctor spot it early.
You might check it if…
- your joints feel stiff for a long while each morning
- small joints in your hands or feet are swollen or sore
- a close relative has rheumatoid arthritis
- a rheumatoid factor test came back positive
What your result may mean
High CCP antibody (IgG): what it may mean
A positive CCP antibody may point to rheumatoid arthritis (RA), a condition where the immune system can attack the lining of the joints. This antibody can be highly specific for RA, and it can appear years before joints start to hurt. Swollen or painful joints in the hands and feet, along with morning stiffness, may follow. RA can be more common in women, and it may ease in pregnancy, then flare in the months after birth. Smoking can raise the chance of RA, and imaging can help check for early joint damage.
Low CCP antibody (IgG): what it may mean
A negative CCP antibody may lower the odds of rheumatoid arthritis (RA), and it can't rule RA out. Some people can have RA without this antibody (seronegative RA), and it may be missing early on. Joint pain can also come from other conditions, such as osteoarthritis or lupus. A clinician may look at rheumatoid factor, inflammation tests such as CRP or sed rate, and an exam of the joints when pain or swelling continues.
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These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.