$12.00
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Autoimmune & inflammation
Cardiolipin antibody (IgM) test
IgM antiphospholipid antibody; combined with IgG can help identify antiphospholipid syndrome.
At a glance
In about 5 days
Most results are ready in about 5 days. Some specialty markers can take up to 21 days.
Check before your draw
This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.
Walk in at Quest
Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.
What it measures
Checks for the IgM type of cardiolipin antibody, which can make blood more likely to clot. It may be tested with the IgG type, and a positive result may be rechecked later, since infections can raise it briefly.
Why it matters for women
Antiphospholipid syndrome, a condition where these antibodies can lead to clots or pregnancy problems, is more common in women and can be found alongside lupus. It can be a treatable cause of repeated miscarriage. A positive result can also mean a higher clot risk with estrogen birth control or during pregnancy.
You might check it if…
- you’ve had repeated miscarriages or a later pregnancy loss
- you’ve had a blood clot without a clear cause
- you had severe preeclampsia in a past pregnancy
- you’re being checked for antiphospholipid syndrome
What your result may mean
High Cardiolipin antibody (IgM): what it may mean
High cardiolipin IgM may mean recent immune activation, and it may add to the picture for antiphospholipid syndrome (APS). The IgM type can be less specific for APS than IgG, and a low-level positive can happen after an infection or even in healthy people. For that reason, a clinician may repeat it a few months later and read it with the IgG type. APS can bring blood clots or pregnancy loss, and it can appear alongside lupus. Clot risk can also climb with estrogen birth control or pregnancy.
Low Cardiolipin antibody (IgM): what it may mean
Low or negative cardiolipin IgM may lower the suspicion of antiphospholipid syndrome (APS), and one result can't clear the question alone. IgM can be just one piece of the puzzle, because some people may test positive only for the IgG type, beta-2 glycoprotein I or lupus anticoagulant. A clinician may read it with those tests, especially after a clot or a pregnancy loss. In someone with no such history, a negative result may need no further testing.
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These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.