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Autoimmune & inflammation

ANA screen test

Antinuclear antibody screen. Immunofluorescence-based ANA screen with automatic titer, pattern, and 11-antibody follow-up if positive.

At a glance

Price

$11.00

Priced per marker, with baseline labs included. You’ll see your total before you pay.

Results

In about 5 days

Most results are ready in about 5 days. Some specialty markers can take up to 21 days.

Preparation

Check before your draw

This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.

Blood draw

Walk in at Quest

Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.

What it measures

Looks for antibodies that target your own cells, a common feature of autoimmune conditions such as lupus. If it’s positive, the lab automatically checks how strong it is and which specific antibodies are involved.

Why it matters for women

Lupus, Sjögren’s, and similar autoimmune conditions mostly affect women, and lupus often begins during the years women can have children. A positive result can also be fairly common in healthy women, so it’s one clue to read alongside your symptoms, not an answer on its own.

You might check it if…

  • you’ve had joint pain, rashes, or fevers without a clear cause
  • your eyes and mouth feel dry most of the time
  • your fingers turn white or blue in the cold
  • a close relative has lupus or another autoimmune condition

What your result may mean

High ANA screen: what it may mean

A positive ANA may mean your immune system is making antibodies that target your own cells, and it may point to an autoimmune condition such as lupus, Sjögren's, scleroderma or autoimmune hepatitis. A higher titer or certain patterns can add weight, and the follow-up antibody panel can help narrow things down. Healthy women can also test positive, and so can older adults and people on some medicines. Joint pain, rashes, dry eyes or mouth, and tiredness can all be clues. Since lupus can begin during the childbearing years, this result may be most useful alongside your symptoms.

Low ANA screen: what it may mean

A negative ANA may lower the odds of a body-wide autoimmune condition such as lupus, and it can't rule one out on its own. With this reflex test, a negative screen can mean the lab stops there, so no titer, pattern or follow-up antibodies may be reported. Some autoimmune conditions, including ones that affect a single organ, can test negative too. If joint pain, rashes, dry eyes or other symptoms continue, a clinician may order more specific antibody tests or repeat this one later.

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No insurance required · HSA/FSA eligible · No subscription

These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.