$6.00
Priced per marker, with baseline labs included. You’ll see your total before you pay.
Autoimmune & inflammation
Rheumatoid factor test
Older RA autoantibody; less specific than CCP but still part of the workup.
At a glance
In about 5 days
Most results are ready in about 5 days. Some specialty markers can take up to 21 days.
Check before your draw
This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.
Walk in at Quest
Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.
What it measures
Rheumatoid factor is an antibody that targets your body’s own proteins. It can be found in rheumatoid arthritis, but it can also show up in other conditions and in some healthy people.
Why it matters for women
Rheumatoid arthritis is more common in women. Rheumatoid factor can also be positive in Sjögren’s, a dry eye and mouth condition that mostly affects women, and in some healthy older adults. That’s why it’s often paired with the CCP antibody test.
You might check it if…
- your joints ache, swell, or feel stiff in the morning
- the same joints hurt on both sides of your body
- your eyes and mouth often feel dry
- a doctor is checking for rheumatoid arthritis
What your result may mean
High Rheumatoid factor: what it may mean
High rheumatoid factor may point to rheumatoid arthritis (RA), but it can also appear with Sjögren's, a dry eye and mouth condition, with long-lasting infections, and with aging. RA and Sjögren's can both be more common in women. Stiff or swollen joints, dry eyes or a dry mouth may be clues, though some healthy older adults can test positive with no symptoms. One result can't name the reason, and the CCP antibody can be more specific for RA.
Low Rheumatoid factor: what it may mean
A negative rheumatoid factor can't rule out rheumatoid arthritis (RA), especially early in the disease, though it may ease concern. Some people with RA can stay negative for this antibody throughout (seronegative RA), and they can still have joint damage. The CCP antibody can be more specific, so a clinician may check it too. If morning stiffness or swollen joints continue, an exam, imaging or inflammation tests such as CRP may help sort out the reason.
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These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.