$28.00
Priced per marker, with baseline labs included. You’ll see your total before you pay.
Autoimmune & inflammation
tTG antibody (IgA) test
Tissue transglutaminase antibody. First-line celiac disease antibody.
At a glance
In about 5 days
Most results are ready in about 5 days. Some specialty markers can take up to 21 days.
Check before your draw
This marker has no preparation tag, but it can still need preparation. Contact us before your draw if you’re not sure.
Walk in at Quest
Your lab order arrives by email. Most Quest locations take walk-ins, so bring it with a photo ID.
What it measures
When gluten, a protein in wheat, barley, and rye, triggers gut damage in celiac disease, your body can make these antibodies. The test works best while you’re still eating gluten.
Why it matters for women
Celiac disease is more common in women, and it can show up as low iron that keeps coming back, early bone thinning, or trouble getting pregnant rather than stomach symptoms. This test relies on IgA, so it’s often paired with a total IgA check.
You might check it if…
- you often get bloating, diarrhea, or belly pain after meals
- low iron keeps coming back without a clear reason
- a close relative has celiac disease
- you’re managing an autoimmune thyroid condition
What your result may mean
High tTG antibody (IgA): what it may mean
High tTG IgA may point to celiac disease, and it can be a strong clue, since this first-line test can be both sensitive and specific for it. Higher levels can add weight, while a small rise can happen with other autoimmune or liver conditions. In women, celiac disease can appear as low iron that keeps coming back, early bone thinning or trouble getting pregnant, sometimes with no stomach symptoms. A clinician may add other celiac tests or a small-bowel biopsy. Ask your clinician before cutting gluten, because that can change follow-up results.
Low tTG antibody (IgA): what it may mean
Low or negative tTG IgA may lower the odds of celiac disease, unless you have IgA deficiency, which can make this test look normal even when celiac is present. A total IgA check can sort that out, and a clinician may switch to the IgG version if your IgA is low. Eating little or no gluten before the draw can also lower the result. If low iron or gut symptoms continue, other reasons may need a look too.
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These notes provide context and do not diagnose a condition. Not yet available in NY, NJ, RI, HI, ND, SD or WV.